产品货号:
Z34107
中文名称:
Beta Amyloid/APP抗体
英文名称:
Anti-Beta Amyloid/APP Antibody (Clone#OTI7G9)
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-Beta Amyloid/APP Antibody (Clone#OTI7G9) |
指标别名 | ABETA;ABPP;amyloid beta 1-42;Amyloid beta A4 protein;amyloid P;amyloid precursor protein;Amyloid-beta precursor protein;Amyloid-beta protein 40;Amyloid-beta protein 42;APP;APPI;Aβ1-42;beta Amyloid |
克隆性 | Monoclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC,IF,FCM |
基因名称 | APP |
克隆号 | OTI7G9 |
抗体来源 | Mouse |
抗体类型 | IgG1 |
免疫原 | Full length human recombinant protein of human APP (NP_000475) produced in HEK293T cell. |
实际分子量 | 87.0KD |
成分 | PBS (pH7.3) containing 1% BSA,50% glycerol and 0.02% sodium azide. |
纯化方式 | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | Stable for 12 months from date of receipt.Store at -20℃ as received. |
背景资料 | Amyloid precursor protein (APP) is an integral membrane protein expressed in many tissues and concentrated in the synapses of neurons.It is mapped to 21q21.3.This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides.Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation,while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease.In addition,two of the peptides are antimicrobial peptides,having been shown to have bacteriocidal and antifungal activities.Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy).Multiple transcript variants encoding several different isoforms have been found for this gene. |
Uniprot ID | P05067 |
基因名全称 | amyloid beta (A4) precursor protein |
蛋白名全称 | Amyloid beta A4 protein |
推荐稀释比 | Western blot (WB) 1:2000 Immunohistochemistry in paraffin section (IHC) 1:50 Immunofluorescence (IF) 1:100 Flow cytometry (FCM) 1:100 |
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